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Why Revolution Medicines (RVMD) Stock Is Down Today

Investivoq PriceTracker

Revolution Medicines (RVMD) is down 3.9% today. Here is some analysis on what might have caused this price movement.

Analysis: The most likely explanation is that investors are taking profits after a huge run-up rather than reacting to clearly negative company-specific news. Revolution Medicines just announced another Phase 3 milestone, but that update may not have been enough to push shares higher after the stock’s sharp gains following its recent drug approval and other pipeline advances.

Details:

  • On October 5, the company said it began treating patients in the Phase 3 RASolute 309 study testing RASONQUE plus zoldonrasib as a first-line treatment for metastatic RAS G12D pancreatic cancer.
  • In mid-September, the company disclosed Breakthrough Therapy designation for RASONQUE in combination with chemotherapy for first-line metastatic pancreatic cancer, reinforcing momentum in the franchise.
  • In late August, RASONQUE won U.S. approval in metastatic pancreatic cancer, giving Revolution Medicines its first approved product and shifting the company into the commercial stage.
  • This could be because expectations are already very high: the stock had already delivered a very large year-to-date gain by early October, so even favorable pipeline progress may have triggered a sell-the-news response.

    • Sources:

    Revolution Medicines, Yahoo Finance, SEC

    Disclaimer: This price movement analysis was generated with the help of AI. Please double-check the information provided for mistakes.

    $RVMD Insider Trading Activity

    RVMD Insider Trades

    $RVMD insiders have traded $RVMD stock on the open market 109 times in the past 6 months. Of those trades, 0 have been purchases and 109 have been sales.

    Here’s a breakdown of recent trading of $RVMD stock by insiders over the last 6 months:

    • MARK A GOLDSMITH (See Remarks) has made 0 purchases and 22 sales selling 230,008 shares for an estimated $40,352,843.
    • STEPHEN MICHAEL KELSEY (See Remarks) has made 0 purchases and 11 sales selling 102,275 shares for an estimated $20,486,119.
    • MARGARET A HORN (Chief Operating Officer) has made 0 purchases and 11 sales selling 104,967 shares for an estimated $16,883,735.
    • LORENCE H. KIM has made 0 purchases and 14 sales selling 73,090 shares for an estimated $14,967,124.
    • JEFF CISLINI (SVP & General Counsel) has made 0 purchases and 10 sales selling 63,182 shares for an estimated $13,070,226.
    • ANTHONY MANCINI (See Remarks) has made 0 purchases and 17 sales selling 33,550 shares for an estimated $6,212,172.
    • ELIZABETH M ANDERSON has made 0 purchases and 5 sales selling 10,143 shares for an estimated $1,958,015.
    • ALAN B. SANDLER (Chief Development Officer) has made 0 purchases and 7 sales selling 6,650 shares for an estimated $1,343,234.
    • JACK ANDERS (Chief Financial Officer) has made 0 purchases and 3 sales selling 6,775 shares for an estimated $1,232,469.
    • SUSHIL PATEL has made 0 purchases and 9 sales selling 5,580 shares for an estimated $1,048,967.

    To track insider transactions, check out Investivoq's insider trading dashboard. You can access data on insider stock transactions through the Investivoq API insider transaction endpoint.

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    $RVMD Hedge Fund Activity

    We have seen 452 institutional investors add shares of $RVMD stock to their portfolio, and 202 decrease their positions in their most recent quarter.

    Here are some of the largest recent moves:

    • DARWIN GLOBAL MANAGEMENT, LTD. added 8,418,804 shares (+380.8%) to their portfolio in Q2 2026, for an estimated $1,576,673,613
    • ADAGE CAPITAL PARTNERS GP, L.L.C. removed 4,878,385 shares (-89.1%) from their portfolio in Q2 2026, for an estimated $913,623,942
    • CAPITAL WORLD INVESTORS added 4,008,244 shares (+inf%) to their portfolio in Q2 2026, for an estimated $750,663,936
    • FMR LLC added 3,736,108 shares (+44.1%) to their portfolio in Q2 2026, for an estimated $699,698,306
    • JPMORGAN CHASE & CO added 3,298,066 shares (+inf%) to their portfolio in Q2 2026, for an estimated $617,661,800
    • BLACKROCK, INC. added 2,483,084 shares (+22.1%) to their portfolio in Q2 2026, for an estimated $465,031,971
    • WELLINGTON MANAGEMENT GROUP LLP removed 2,184,404 shares (-36.2%) from their portfolio in Q2 2026, for an estimated $409,095,181

    To track hedge funds' stock portfolios, check out Investivoq's institutional holdings dashboard. You can access data on hedge funds moves and 13F filings through the Investivoq API 13F endpoint.

    $RVMD Price Targets

    Multiple analysts have issued price targets for $RVMD recently. We have seen 14 analysts offer price targets for $RVMD in the last 6 months, with a median target of $195.0.

    Here are some recent targets:

    • Michael Schmidt from Guggenheim set a target price of $235.0 on 07/09/2026
    • Robert Burns from HC Wainwright & Co. set a target price of $195.0 on 07/06/2026
    • Joseph Catanzaro from Mizuho set a target price of $215.0 on 07/06/2026
    • Robert Driscoll from Wedbush set a target price of $181.0 on 07/02/2026
    • Gregory Renza from Truist Securities set a target price of $210.0 on 06/30/2026
    • Ami Fadia from Needham set a target price of $235.0 on 06/29/2026
    • Cory Kasimov from Evercore ISI Group set a target price of $220.0 on 06/10/2026

    This article is not financial advice. See Investivoq's disclaimers for more information. Note that there may be inaccuracies due to mistakes in ticker-mapping, and other anomalies.