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Karyopharm Therapeutics Inc Stock Short Interest Rises to 36.48%

Investivoq ShortTracker

Karyopharm Therapeutics Inc short interest was 36.48% of the float on October 30th, according to new data we received from Benzinga. Short interest totaled 8,232,156 shares, which was an increase of 13.28% from October 15th.

It is estimated that it would take 1.09 days for short sellers to buy back their shares, with current trading volumes.

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Karyopharm Therapeutics Inc Hedge Fund Activity

We have seen 66 institutional investors add shares of Karyopharm Therapeutics Inc stock to their portfolio, and 31 decrease their positions in their most recent quarter.

Here are some of the largest recent moves:

  • COMMODORE CAPITAL LP removed 1,950,000 shares (-100.0%) from their portfolio in Q2 2026, for an estimated $19,051,500
  • ACORN CAPITAL ADVISORS, LLC added 1,230,287 shares (+427.4%) to their portfolio in Q2 2026, for an estimated $12,019,903
  • BLACKROCK, INC. added 1,173,900 shares (+479.3%) to their portfolio in Q2 2026, for an estimated $11,469,003
  • IKARIAN CAPITAL, LLC removed 733,435 shares (-100.0%) from their portfolio in Q2 2026, for an estimated $7,165,659
  • UBS GROUP AG added 610,346 shares (+172.6%) to their portfolio in Q3 2026, for an estimated $744,622
  • NEA MANAGEMENT COMPANY, LLC added 576,780 shares (+inf%) to their portfolio in Q2 2026, for an estimated $5,635,140
  • TWO SIGMA INVESTMENTS, LP added 544,032 shares (+359.7%) to their portfolio in Q2 2026, for an estimated $5,315,192

To track hedge funds' stock portfolios, check out Investivoq's institutional holdings dashboard. You can access data on hedge funds moves and 13F filings through the Investivoq API 13F endpoint.

Karyopharm Therapeutics Inc Insider Trading Activity

KPTI Insider Trades

Karyopharm Therapeutics Inc insiders have traded $KPTI stock on the open market 9 times in the past 6 months. Of those trades, 0 have been purchases and 9 have been sales.

Here’s a breakdown of recent trading of $KPTI stock by insiders over the last 6 months:

  • RICHARD A. PAULSON (President and CEO) sold 2,203 shares for an estimated $20,928
  • STUART POULTON (EVP, Chief Development Officer) has made 0 purchases and 2 sales selling 592 shares for an estimated $5,170.
  • RESHMA RANGWALA (EVP & Chief Medical Officer) sold 408 shares for an estimated $3,876
  • SOHANYA ROSHAN CHENG (EVP & Chief Commercial Officer) sold 324 shares for an estimated $3,078
  • MICHAEL MANO (EVP, CLO&Secretary) sold 266 shares for an estimated $2,527
  • KRISTIN ABATE (Chief Accounting Officer) has made 0 purchases and 3 sales selling 4,860 shares for an estimated $2,188.

To track insider transactions, check out Investivoq's insider trading dashboard. You can access data on insider stock transactions through the Investivoq API insider transaction endpoint.

This article is not financial advice. See Investivoq's disclaimers for more information. Note that there may be inaccuracies due to mistakes in ticker-mapping, and other anomalies.

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